Description
IOS-1 FOR SALE .
Antagonist of macrophage migration inhibitory factor (MIF, a pro-inflammatory cytokine). Displays anti-inflammatory activity. Increases survival in severe sepsis 1. Inhibits airway remodeling in mouse asthma model 2. Blocks MIF-induced autophagy 3. Inhibits experimental autoimmune diabetes in a mouse model, reducing islet antigen-specific proliferative responses and adhesive cell-cell interactions 4. Active in cellular and mouse models. Reverses Amyloid Beta-induced toxicity in mouse and human neuronal cell lines 5. IOS-1 FOR SALE .
