Description
Tyrosine kinase inhibitor specific for bcr-abl (IC50 = 38 nM) 1, PDGF-R (IC50 = 0.3 μM)1 and c-kit (IC50 = 0.1 μM) 2. It is a clinically useful anti-cancer drug approved for the treatment of chronic myelogenous leukemia, gastrointestinal stromal tumors as well as several other cancers 3. Lowers Amyloid Beta levels by indirect inhibition of gamma-secretase without inhibiting gamma-secretase processing of Notch1 4. Imatinib Mesylate For Sale
