Description

Product background: Beta-Amyloid peptides (A-beta), the major constituent of amyloid plaques in the brains of Alzheimer’s patients, is thought to be a primary contributor to Alzheimer’s Disease (AD). Beta-Amyloid (1-42) Preformed Fibrils

About the product: Expressed recombinantly in E. coli, human Beta-Amyloid (1-42) is purified to our highest standards to ensure batch-to-batch consistency in both purity and quality. The human Beta-Amyloid is then made into preformed fibrils with their presence and length being confirmed by transmission electron microscopy (TEM) and thioflavin fluorescence assay. Beta-Amyloid (1-42) Preformed Fibrils

Applications: These human Beta-Amyloid (1-42) fibrils are sold as a frozen 4mg/mL solution of total protein. The fibrils may be suitable for either in vitro or in vivo requirements such as fibril stability, seeding experiments, aggregation studies, or preformed fibril injections. Beta-Amyloid preformed fibrils may also be used as an amyloid plaque model in any other study of Alzheimer’s Disease.

Beta-Amyloid (1-42) Preformed Fibrils