Description
Product Background: Alpha-Synuclein (α-Synuclein) is a presynaptic protein found to be a major component of Parkinson’s Disease (PD) aggregates and is implicated in the pathogenesis of PD and related neurodegenerative disorders. Alpha-Synuclein 98AA Preformed Fibrils
About the product: Expressed recombinantly in E. coli, Alpha-Synuclein 98 is a splicing variant that lacks exons 3 (G41-T54) and 5 (N103-E130) and is purified to our highest standards to ensure batch-to-batch consistency in both purity and quality. This form of human Alpha-Synuclein was then formed into fibrils according to rPeptide’s proprietary methods. Fibril formation is determined by TEM and thioflavin assay. Alpha-Synuclein 98AA Preformed Fibrils
Applications: The Alpha-Synuclein 98 fibrils are sold in 200mM Tris, 250mM NaCl, pH 7.4 and may be suitable for experimental use or as controls in aggregation kinetics, fibril morphology, seeding experiments, or in vivo imaging.
Alpha-Synuclein 98AA Preformed Fibrils
