Description
FK-506 induces immunosuppression by inhibiting T cell proliferation. Inhibits FKBP12 and calcineurin (IC50ca. 1 nM) 1. Reduces neuroinflammation and neuro-degeneration in an alpha-synuclein-based rat model of Parkinson’s disease 2. Increases the rate of axonal regeneration following crush injury in a rat model 3. Cell permeable.
