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Alpha-Synuclein, Delta-NAC

$150.00

  • Size: 0.5 mg
  • Physical State: White lyophilized powder
  • Temperature Storage: -20°C
  • Temperature Shipping: Ambient
  • Sequence:
    MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK GTEIWMKKDQ LGKNEEGAPQ EGILEDMPVD PDNEAYEMPS EEGYQDYEPE A
  • Source: Recombinant. A DNA sequence encoding a deletion mutant of Alpha-Synuclein that lacks the NAC region (amino acid 61-95). 6 amino acids were added as a linker.
  • Purity: >95% by SDS-PAGE
  • Molecular Mass: 11,935 Da theoretical
Category:

Description

Product background: Alpha-Synuclein (α-Synuclein) is a presynaptic protein found to be a major component of Parkinson’s Disease (PD) aggregates and is implicated in the pathogenesis of PD and related neurodegenerative disorders.

About the product: Expressed recombinantly in E. coli, human Alpha-Synuclein Delta NAC does not have the NAC region (amino acids 61-140) and is purified to our highest standards to ensure batch-to-batch consistency in both purity and quality.

Applications: Human Alpha-Synuclein Delta NAC is sold in 20mM Tris, 100mM NaCl, pH 7.4 to ensure a highly monomeric starting material that may be suited to aggregation studies, seeding experiments, molecular standards, and more.